The story of British officer T.E. Lawrence's mission to aid the Arab tribes in their revolt against the Ottoman Empire during the First World War. Lawrence becomes a flamboyant, messianic figure in the cause of Arab unity but his psychological instability threatens to undermine his achievements.

Set during the period of growing influence of the Indian independence movement in the British Raj, the story begins with the arrival in India of a British woman, Miss Adela Quested, who is joining her fiancé, a city magistrate named Ronny Heaslop. She and Ronny's mother, Mrs. Moore, befriend an Indian doctor, Aziz H. Ahmed.

Returning home from a shopping trip to a nearby town, bored suburban housewife Laura Jesson is thrown by happenstance into an acquaintance with virtuous doctor Alec Harvey. Their casual friendship soon develops during their weekly visits into something more emotionally fulfilling than either expected, and they must wrestle with the potential havoc their deepening relationship would have on their lives and the lives of those they love.