A mild-mannered man becomes a local hero through an act of violence, but it brings forth consequences with connection to a dangerous world, one which will shake his carefully constructed life to its very core.

A scientist is spurred by the death of his friend to find a cure for diabetes, but can he take on the might of the pharma mafia and succeed in his mission?

An enterprising youngster in a slum wants his people to lead a life of dignity, but has to take on an ambitious capitalist, who only wants to dominate his field.

Picking up the storyline from where Singam ended, Duraisingam (Suriya) has gone undercover after meeting the Home Minister and is working as an NCC officer in a school in Thoothukudi. The only people who know about this operation are the Chief Minister and Home Minister apart from himself.

The film's plot revolves around Kanthasamy (played by Vikram), who is a Income Tax officer in the CBI, and his friends, granting the wishes of the needy who write letters to a local Lord Muruga temple by disguising himself as an anthropomorphic chicken. During a CBI income tax raid, he discovers a stash of black money owned by Ponnusamy (played by Ashish Vidyarthi), a rich and corrupted entrepreneur. Ponnusamy pretends to be paralysed to escape the questioning. Angered by the news that her father is paralysed, Ponnusamy's daughter, Subbulakshmi (played by Shriya Saran) goes after Kanthasamy to seek revenge by pretending to be in love with him. Kanthasamy, knowing Subbulakshmi's real intentions plays along in the game. This forms a cat and mouse chase between the two.

A bloody power struggle erupts between three brothers who are vying to take over the family business following the death of their father.